MoSMB used in HCI platform to support VDI
SMB3 server used in Hyper-coverged Infrastructure HCI to support Hyper-V VDI use case.
Why SMB 3.0
For most Microsoft shops you need SMB3 if you want to use Hyper-V SMB 3.0 also introduces several security enhancements, such as end-to-end encryption and a new AES based signing algorithm. Amongst the various new features available in SMB3 that enable enterprise